Modeling Without a Gold Standard: Stratification with Stratum-Dependent Parameters
DOI:
https://doi.org/10.57805/revstat.v12i1.145Keywords:
absence of a gold standard, diagnostic test, identifiability, sample size, stratificationAbstract
Bayesian latent-class models have been widely applied for assessing the performance of diagnostic tests in the absence of a gold standard. We provide a short discussion on identifiability issues appearing under the absence of a gold standard, and construct an extension of the well-known Hui–Walter stratification model which allows for stratumdependent parameters. We illustrate our approach using a Chagas disease case study on blood donors from Brazil.
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Copyright (c) 2014 REVSTAT-Statistical Journal
This work is licensed under a Creative Commons Attribution 4.0 International License.